Spray for Premature Ejaculation Helps

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Jan. 26, 2007 — An anesthetic spray more than doubles the “lasting”time for men with premature ejaculation, according to a study by the companythat makes the experimental spray.

The metered-dose, aerosol spray is a mixture of the anesthetics lidocaineand prilocaine. It is spritzed onto the tip of the penis 15 minutes beforesex.

Before using the spray, the 54 heterosexual men in the study ejaculated, onaverage, one minute after vaginal penetration.

In the test, on four occasions, half the men used the anesthetic spray 15minutes before sex, the other half a placebo with no active ingredients.

The men or their partners used a stopwatch to measure the time from vaginalpenetration to ejaculation.

The results:

  • Lasting time increased to two minutes or more for 55% of the men who gotthe spray and 35% of the men who got the placebo.
  • Lasting time increased to three minutes or more for 40% of the men who gotthe spray and 13% of the men who got the placebo.
  • Lasting time increased to four minutes or more for 20% of the men who gotthe spray and 13% of the men who got the placebo.
  • On average, men who got the spray lasted 2.4 times longer than those whogot the placebo.

Premature ejaculation isn’t defined by a specific time until ejaculation.According to the Diagnostic and Statistical Manual of Mental Disorders IV(DSM-IV), premature ejaculation is “persistent or recurrent ejaculationwith minimal sexual stimulation before, on, or shortly after penetration andbefore the person wishes it.”

About 70% of men who used the spray and just under 50% of the men who usedthe placebo said they had longer time to ejaculation.

About 60% of the female partners of men who used the spray, and about 30% ofthe partners of the men who used the placebo, said the men had better controlover their ejaculation.

The spray is called TEMPE — topical eutectic mixture for prematureejaculation — by manufacturer Plethora Solutions Ltd. London, which funded thestudy. It is not yet available on the market.

“TEMPE ‘as required’ has the potential to offer a convenient, noveltreatment option for men with premature ejaculation,” conclude researchersWallace C. Dinsmore, MD, of Royal Victoria Hospital, Belfast, Northern Ireland,and colleagues.

The spray had few side effects.

Four of the 26 men who used TEMPE did report side effects. Three hadnumbness of the penis, and one reported erectile dysfunction.

Only one of the men’s sex partners reported a side effect: a mild burningsensation during intercourse.

Emla, from AstraZeneca, is also a mixture of lidocaine and prilocaine. Itcomes in a cream formulation and must be used with a condom. TEMPE does notrequire condom use.

The study appears in the February issue of the urology journal BJUInternational.

Copyright 2020 Nexstar Broadcasting, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.

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