The 2016 NFL season officially kicks-off Thursday night in a re-match of Super Bowl 50.
The Carolina Panthers take on the Super Bowl Champions Denver Broncos in Denver on WETM-TV (NBC).
The Broncos took home the Lombardi Trophy in February after defeating the Panthers 24 to 10.
New rules this season include automatic ejections for players with two unsportsman-like conduct fouls, moving the spot of a touchback to the 25-yard line, and banning all chop blocks.
The defending super bowl champions have hosted the season opener since 2004 and have won all but two in that time.
The season kicks off at 8:30 p.m. on WETM-TV, followed by 18 News at Eleven.